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Tiny wasp’s shocking reproductive trick may transform global agriculture

Scientists have shed new light on the evolution of an important species of wasp – and believe that the findings could help improve the effectiveness of natural pest control.

Dr Rebecca Boulton, from the University of Stirling, has shown, for the first time, thatLysiphlebus fabarum- a tiny species of wasp – can reproduce with or without a mate. This discovery challenges the previous assumption that asexual females could not mate and produce offspring sexually.

Significantly, the wasps lay their eggs inside small sap-sucking insects called aphids before consuming their host from the inside out — meaning that they are natural pest controllers.

Lysiphlebus fabarumis known to have both sexual and asexual populations but, until now, it was not known whether asexual females could reproduce sexually with males. The discovery opens up new possibilities for improving biological pest control.

Many species of parasitoid wasps are mass-reared and released as a natural alternative to pesticides because they lay their eggs on or in other species, many of which are pests, before the developing wasp larvae consumes their host, killing it in the process.

Asexual reproduction makes it easy to produce large numbers of wasps, but these need to be suitably adapted to local pests and environments to be effective. Currently,Lysiphlebus fabarumis not used commercially despite being found worldwide and naturally targeting aphids.

Developing an understanding of how the species reproduce could help boost genetic diversity in commercially reared lines, making future biocontrol agents more resilient and better adapted.

Dr Boulton, a lecturer in Biological and Environmental Sciences at the University's Faculty of Natural Sciences, led the study. She said: "In an evolutionary sense, facultative sex seems like a perfect strategy – asexual reproduction is highly efficient, and takes away the costs of finding a mate as well as the risks of failing to find one.

"But sex is really important for evolution. When females reproduce asexually they don't mix their genes up with any others which limits the potential for evolution to happen.

"If the environment changes, asexual species may be unable to adapt in the same way that sexuals can.

"Facultative sex brings the efficiency of asexual reproduction with the evolutionary benefits of sex and so has been touted as the best of both worlds.

"The results of my study show that there might be hidden costs to facultative sex though as it reduces female wasps' reproductive success, and this might limit how frequently it occurs in nature.

"The wasps that I studied are an important natural enemy of aphids, they aren't currently commercially reared, but they are found globally.

"My findings could be used to develop new biocontrol agents that can be used to control aphids throughout the world, harnessing their natural reproductive behavior to ensure that they are adapted to the hosts and environments that are specific to different regions."

Dr Boulton reared the wasps in a Controlled Environment Facility (CEF) at the University and had initially planned to put asexual and sexual wasps together, in direct competition, to see which parasitized the most aphids.

However, in the early stages of these experiments she realized the female asexual wasps were behaving unexpectedly and were mating with males from the sexual population.

This led to a change in strategy, as she started to record this behavior in more detail, before carrying out wasp paternity testing to see whether the asexual females were just mating or actually fertilizing eggs.

Once it confirmed that the asexual wasps were engaging in facultative sex, Dr Boulton carried out an experiment where asexual females either mated or didn't, before examining how successful these females, and their daughters, were at parasitizing aphids.

The study involved putting around 300 wasps, each around 1mm long, in their own petri dish with a colony of sap-sucking aphids and counting how many were parasitized.

Lysiphlebus fabarumwasps only live a few days but spend two weeks developing as larvae on their hosts.

The entire experiment, which was carried out across two generations of wasps, took six weeks to run.

On completion Dr Boulton extracted DNA from the wasps and sent it to be paternity tested. When the results were returned it was clear that the asexual wasps which mated were, in most cases, reproducing sexually as their offspring had bits of DNA that were only found in the fathers.

The study, Is facultative sex the best of both worlds in the parasitoid wasp Lysiphlebus fabarum? is published in the Royal Society of Open Science.

It was funded through a BBSRC Discovery fellowship.

Professor Anne Ferguson-Smith, Executive Chair of BBSRC, said: "This is an exciting example of how BBSRC's Discovery Fellowships are helping talented early career researchers explore fundamental questions in bioscience with real-world relevance.

"Dr Boulton's work, which measures the costs of sex in this predominantly asexual parasitoid wasp, opens up promising avenues for more sustainable pest control. Supporting curiosity-driven research like this not only strengthens the UK's research base, but helps drive innovation that benefits the environment, food systems and society at large."

Materialsprovided byUniversity of Stirling.Note: Content may be edited for style and length.

Galactic mystery: Why massive stars struggle to form in the Milky Way’s center

New research led by Dr. James De Buizer at the SETI Institute and Dr. Wanggi Lim at IPAC at Caltech revealed surprising results about the rate at which high-mass stars form in the Galactic Center of the Milky Way. The researchers based their study primarily on observations from NASA's now-retired SOFIA airborne observatory, focusing on three star-forming regions — Sgr B1, Sgr B2, and Sgr C — located at the heart of the Galaxy. Although the central part of our Galaxy has a much higher density of star-forming material than the rest of the Milky Way, in the Galactic Center, the current rate of formation of massive stars (those larger than 8 times the mass of our Sun) appears to be lower compared to the rest of the Galaxy.

The team compared these three Galactic Center star-forming regions to similar-sized regions further out in the Galaxy, including those closer to our Sun, and confirmed that the rate of star formation is below average near the Galactic Center. Their study finds that despite the Galactic Center's dense clouds of gas and dust, conditions that typically produce stars with high masses, these star-forming regions struggle to form high-mass stars. Furthermore, the studied areas appear to lack sufficient material for continued star formation, suggesting such regions effectively produce just one generation of stars, unlike typical star-forming regions.

"Recent studies have concluded that star formation is likely depressed near the Galactic Center, and even that there may be no present star formation occurring there," said De Buizer, lead author of the study. "Since presently-forming massive stars are brightest at long infrared wavelengths, we obtained the highest resolution infrared images of our Galaxy's central-most star-forming regions. The data show that, contrarily, massive stars are presently forming there, but confirm at a relatively low rate."

The study suggests that the reason for the slowdown in star formation is due to the extreme conditions in the Galactic Center. These regions orbit swiftly around the black hole at the center of the Galaxy, interacting with older stars and possibly with other material falling toward the black hole. These conditions could inhibit gas clouds from holding together long enough to form stars in the first place and prevent those that do form stars from staying together long enough for continued future star formation.

However, Sgr B2 appears to be the exception. Although its rate of present massive star formation is unusually low, like the other Galactic Center regions studied, it seems to have maintained its reservoir of dense gas and dust, allowing for a future emergent star cluster to be born.

Traditionally, astronomers have viewed giant H II regions — large clouds of gas, mainly hydrogen, in space like Sgr B1 and Sgr C — as hosts of massive star clusters still embedded in their birth clouds. This study challenges that assumption. The team argues these two regions may not fit the classical definition at all, or they may represent a new, previously unrecognized category of stellar nursery.

Enshrouded in gas and dust that obscure these star-forming regions from view in all but the longest infrared wavelengths, SOFIA's high-resolution infrared eyes allowed the team to identify more than six dozen presently-forming massive stars within the Galactic Center regions. However, these regions formed fewer stars — and topped out at a lower stellar mass — than the Galactic average.

"These Galactic Center star-forming regions are in many ways very similar to the massive star-forming regions in the relatively calm backwaters of our galaxy," said Lim. "However, the most massive stars we are finding in these Galactic Center regions, though still remarkably large, fall short in both size and quantity compared to those found in similar regions elsewhere in our Galaxy. Furthermore, such star-forming regions typically hang on to large reservoirs of star-forming material and continue to produce multiple epochs of stars, but that appears to not be the case for these Galactic Center regions."

Lim will present the results of this study at the 246th meeting of the American Astronomical Society in Anchorage, AK.

Materialsprovided bySETI Institute.Note: Content may be edited for style and length.

Single psilocybin trip delivers two years of depression relief for cancer patients

New results from a clinical trial reveal that a single dose of psilocybin — a naturally occurring psychedelic compound found in mushrooms — can provide sustained reductions in depression and anxiety in individuals with cancer suffering from major depressive disorder. The findings are published by Wiley online inCANCER, a peer-reviewed journal of the American Cancer Society.

People with cancer often struggle with depression. In this phase 2 trial, 28 patients with cancer and major depressive disorder received psychological support from a therapist prior to, during, and following a single 25-mg dose of psilocybin.

During clinical interviews conducted 2 years later, 15 (53.6%) patients demonstrated a significant reduction in depression, and 14 (50%) had sustained depression reduction as well as remission. Similarly, psilocybin reduced anxiety for 12 (42.9%) patients at 2 years.

An ongoing randomized, double-blind trial is currently evaluating up to two doses of 25 mg of psilocybin versus placebo as treatment for depression and anxiety in patients with cancer. This study is building on the single-dose study in an effort to bring a larger majority of the patients into remission of depression and anxiety.

"One dose of psilocybin with psychological support to treat depression has a long-term positive impact on relieving depression for as much as 2 years for a substantial portion of patients with cancer, and we're exploring whether repeating the treatment resolves depression for more than half of the patients," said lead author Manish Agrawal, MD, of Sunstone Therapies. "If randomized testing shows similar results, this could lead to greater use of psilocybin to treat depression in patients with cancer."

Materialsprovided byWiley.Note: Content may be edited for style and length.

Scientists discover llama antibodies that shut down COVID — and its future variants

Scientists have discovered a unique class of small antibodies that are strongly protective against a wide range of SARS coronaviruses, including SARS-CoV-1 and numerous early and recent SARS-CoV-2 variants. The unique antibodies target an essential highly conserved site at the base of the virus's spike protein, effectively clamping it shut and preventing the virus from infecting cells. The findings, published inNature Communications, offer a promising route to developing broad-spectrum antiviral treatments that could remain effective against future viral variants.

SARS-CoV-2, the virus behind COVID-19, continues to be a potential threat as it evolves into newer variants that are resistant to currently approved antibody therapies. Resistance largely emerges because antibodies typically target virus regions, such as the receptor binding domain of the spike protein, that also frequently mutate, enabling escape from antibody recognition.

To address this, a research team led by Prof. Xavier Saelens and Dr. Bert Schepens at the VIB-UGent Center for Medical Biotechnology explored a different strategy by focusing on one of the more stable subunits of the spike protein. The so-called S2 subunit is critical for the virus's ability to fuse with host cells, a process essential for infection, and it is more conserved across different coronaviruses.

The team turned to llamas (more specifically a llama called Winter). Llamas generate so-calledsingle-domain antibodies, also known as VHHs or nanobodies, that are much smaller than the antibodies generated by most animals, including humans. The researchers identified several llama antibodies that strongly neutralize a broad panel of SARS coronaviruses.

What makes these antibodies particularly promising is their unique mode of action: they act like a molecular clamp. They latch onto the poorly exposed, highly conserved region (a coiled coil of 3 alpha helices) at the base of the virus's spike protein. In doing so, they lock the spike protein in its original shape, physically preventing it from unfolding into the form the virus needs to infect cells.

The antibodies showed strong protection against infection in lab animals, even at low doses. And when researchers attempted to force the virus to evolve resistance, the virus struggled, producing only rare escape variants that were much less infectious. This points to a powerful, hard-to-evade treatment option.

"This region is so crucial to the virus that it can't easily mutate without weakening the virus itself," explains Schepens, senior author of the study. "That gives us a rare advantage: a target that's both essential and stable across variants."

This discovery marks a significant advancement in the quest for durable and broadly effective antiviral therapies, offering hope for treatments that can keep pace with viral evolution.

"The combination of high potency, broad activity against numerous viral variants, and a high barrier to resistance is incredibly promising," adds Saelens. "This work provides a strong foundation for developing next-generation antibodies that could be vital in combating not only current but also future coronavirus threats."

This research was made possible with financial support from, among others, the Research Foundation – Flanders (FWO), EOS, EU Horizon 2021, and Exevir.

Materialsprovided byVlaams Instituut voor Biotechnologie.Note: Content may be edited for style and length.

Your brain has a hidden beat — and smarter minds sync to it

When the brain is under pressure, certain neural signals begin to move in sync – much like a well-rehearsed orchestra. A new study from Johannes Gutenberg University Mainz (JGU) is the first to show how flexibly this neural synchrony adjusts to different situations and that this dynamic coordination is closely linked to cognitive abilities. "Specific signals in the midfrontal brain region are better synchronized in people with higher cognitive ability – especially during demanding phases of reasoning," explained Professor Anna-Lena Schubert from JGU's Institute of Psychology, lead author of the study recently published in theJournal of Experimental Psychology: General.

The researchers focused on the midfrontal area of the brain and the measurable coordination of the so-called theta waves. These brainwaves oscillate between four and eight hertz and belong to the group of slower neural frequencies. "They tend to appear when the brain is particularly challenged such as during focused thinking or when we need to consciously control our behavior," said Schubert, who heads the Analysis and Modeling of Complex Data Lab at JGU.

Being able to focus even next to a buzzing phone

The 148 participants in the study, aged between 18 and 60, first completed tests assessing memory and intelligence before their brain activity was recorded using electroencephalography (EEG). This method measures tiny electrical signals in the brain using electrodes placed on the scalp and is a well-established technique for gaining precise insights into cognitive processes. During EEG recording, participants completed three mentally demanding tasks designed to assess cognitive control.

The researchers were interested in the participants' ability to flexibly shift between changing rules, which is an essential aspect of intelligent information processing. For example, participants had to press a button to decide whether a number was even or odd, and moments later whether it was greater or less than five. Each switch of rules required rapid adjustment of mental strategies – a process that allowed researchers to closely observe how the brain's networks coordinate in real time.

As a result, individuals with higher cognitive abilities showed especially strong synchronization of theta waves during crucial moments, particularly when making decisions. Their brains were better at sustaining purposeful thought when it mattered most. "People with stronger midfrontal theta connectivity are often better at maintaining focus and tuning out distractions, be it that your phone buzzes while you're working or that you intend to read a book in a busy train station," explained Schubert.

Professor Anna-Lena Schubert was particularly surprised by how closely this brain rhythm coordination was tied to cognitive abilities. "We did not expect the relationship to be this clear," she said. What mattered most was not continuous synchronization, but the brain's ability to adapt its timing flexibly and contextually – like an orchestra that follows a skilled conductor. The midfrontal region often sets the tone in this coordination but works in concert with other areas across the brain. This midfrontal theta connectivity appears to be particularly relevant during the execution of decisions, however not during the preparatory mental adjustment to new task rules.

Previous EEG studies on cognitive ability mostly examined activity in isolated brain regions. In contrast, this study took a network-level approach, examining how different areas interact across multiple tasks to identify stable, overarching patterns. The findings show that individual differences in cognitive ability are linked to the brain's dynamic network behavior.

"Potential applications such as brain-based training tools or diagnostics are still a long way off," emphasized Schubert. "But our study offers important groundwork for understanding how intelligence functions at a neural level." A follow-up study, now seeking participants aged 40 and older from the Rhine-Main region, will explore which biological and cognitive factors further support this kind of efficient brain coordination and the role of additional cognitive abilities, such as processing speed and working memory.

Materialsprovided byJohannes Gutenberg Universitaet Mainz.Note: Content may be edited for style and length.

Magnetic mayhem at the sun’s poles: First images reveal a fiery mystery

Thanks to its newly tilted orbit around the Sun, the European Space Agency-led Solar Orbiter spacecraft is the first to image the Sun's poles from outside the ecliptic plane. Solar Orbiter's unique viewing angle will change our understanding of the Sun's magnetic field, the solar cycle and the workings of space weather.

Any image you have ever seen of the Sun was taken from around the Sun's equator. This is because Earth, the other planets, and all other modern spacecraft orbit the Sun within a flat disc around the Sun called the ecliptic plane. By tilting its orbit out of this plane, Solar Orbiter reveals the Sun from a whole new angle.

The video titled 'EUI video SolarOrbiter Sun south pole' compares Solar Orbiter's view (in yellow) with the one from Earth (grey), on 23 March 2025. At the time, Solar Orbiter was viewing the Sun from an angle of 17° below the solar equator, enough to directly see the Sun's south pole. Over the coming years, the spacecraft will tilt its orbit even further, so the best views are yet to come.

"Today we reveal humankind's first-ever views of the Sun's pole" says Prof. Carole Mundell, ESA's Director of Science. "The Sun is our nearest star, giver of life and potential disruptor of modern space and ground power systems, so it is imperative that we understand how it works and learn to predict its behaviour. These new unique views from our Solar Orbiter mission are the beginning of a new era of solar science."

All eyes on the Sun's south pole

A collage shows the Sun's south pole as recorded on March 16-17, 2025, when Solar Orbiter was viewing the Sun from an angle of 15° below the solar equator. This was the mission's first high-angle observation campaign, a few days before reaching its current maximum viewing angle of 17°.

The images shown in the collage were taken by three of Solar Orbiter's scientific instruments: the Polarimetric and Helioseismic Imager (PHI), the Extreme Ultraviolet Imager (EUI), and the Spectral Imaging of the Coronal Environment (SPICE) instrument. Click on the image to zoom in and see video versions of the data.

"We didn't know what exactly to expect from these first observations – the Sun's poles are literally terra incognita," says Prof. Sami Solanki, who leads the PHI instrument team from the Max Planck Institute for Solar System Research (MPS) in Germany.

The instruments each observe the Sun in a different way. PHI images the Sun in visible light (top left of the collage) and maps the Sun's surface magnetic field (top centre). EUI images the Sun in ultraviolet light (top right), revealing the million-degree charged gas in the Sun's outer atmosphere, the corona. The SPICE instrument (bottom row) captures light coming from different temperatures of charged gas above the Sun's surface, thereby revealing different layers of the Sun's atmosphere.

By comparing and analysing the complementary observations made by these three imaging instruments, we can learn about how material moves in the Sun's outer layers. This may reveal unexpected patterns, such as polar vortices (swirling gas) similar to those seen around the poles of Venus and Saturn.

These groundbreaking new observations are also key to understanding the Sun's magnetic field and why it flips roughly every 11 years, coinciding with a peak in solar activity. Current models and predictions of the 11-year solar cycle fall short of being able to predict exactly when and how powerfully the Sun will reach its most active state.

Messy magnetism at solar maximum

One of the first scientific findings from Solar Orbiter's polar observations is the discovery that at the south pole, the Sun's magnetic field is currently a mess. While a normal magnet has a clear north and south pole, the PHI instrument's magnetic field measurements show that both north and south polarity magnetic fields are present at the Sun's south pole.

This happens only for a short time during each solar cycle, at solar maximum, when the Sun's magnetic field flips and is at its most active. After the field flip, a single polarity should slowly build up and take over the Sun's poles. In 5-6 years from now, the Sun will reach its next solar minimum, during which its magnetic field is at its most orderly and the Sun displays its lowest levels of activity.

"How exactly this build-up occurs is still not fully understood, so Solar Orbiter has reached high latitudes at just the right time to follow the whole process from its unique and advantageous perspective," notes Sami.

PHI's view of the full Sun's magnetic field puts these measurements in context (see 'PHI_south-pole-Bmap' and 'PHI_global-Bmap_20250211-20250429'). The darker the colour (red/blue), the stronger the magnetic field is along the line of sight from Solar Orbiter to the Sun.

The strongest magnetic fields are found in two bands either side of the Sun's equator. The dark red and dark blue regions highlight active regions, where magnetic field gets concentrated in sunspots on the Sun's surface (photosphere).

Meanwhile, both the Sun's south and north poles are speckled with red and blue patches. This demonstrates that at small scales, the Sun's magnetic field has a complex and ever-changing structure.

SPICE measures movement for the first time

Another interesting 'first' for Solar Orbiter comes from the SPICE instrument. Being an imaging spectrograph, SPICE measures the light (spectral lines) sent out by specific chemical elements – among which hydrogen, carbon, oxygen, neon and magnesium – at known temperatures. For the last five years, SPICE has used this to reveal what happens in different layers above the Sun's surface.

Now for the first time, the SPICE team has also managed to use precise tracking of spectral lines to measure how fast clumps of solar material are moving. This is known as a 'Doppler measurement', named after the same effect that makes passing ambulance sirens change pitch as they drive by.

The resulting velocity map reveals how solar material moves within a specific layer of the Sun. By comparing the SPICE doppler and intensity maps, you can directly compare the location and movement of particles (carbon ions) in a thin layer called the 'transition region', where the Sun's temperature rapidly increases from 10 000 °C to hundreds of thousands of degrees.

The SPICE intensity map reveals the locations of clumps of carbon ions. The SPICE doppler map includes the blue and red colours to indicate how fast the carbon ions are moving towards and away from the Solar Orbiter spacecraft, respectively. Darker blue and red patches are related to material flowing faster due to small plumes or jets.

Crucially, Doppler measurements can reveal how particles are flung out from the Sun in the form of solar wind. Uncovering how the Sun produces solar wind is one of Solar Orbiter's key scientific goals.

"Doppler measurements of solar wind setting off from the Sun by current and past space missions have been hampered by the grazing view of the solar poles. Measurements from high latitudes, now possible with Solar Orbiter, will be a revolution in solar physics," says SPICE team leader, Frédéric Auchère from the University of Paris-Saclay (France).

These are just the first observations made by Solar Orbiter from its newly inclined orbit, and much of this first set of data still awaits further analysis. The complete dataset of Solar Orbiter's first full 'pole-to-pole' flight past the Sun is expected to arrive on Earth by October 2025. All ten of Solar Orbiter's scientific instruments will collect unprecedented data in the years to come.

"This is just the first step of Solar Orbiter's 'stairway to heaven': in the coming years, the spacecraft will climb further out of the ecliptic plane for ever better views of the Sun's polar regions. These data will transform our understanding of the Sun's magnetic field, the solar wind, and solar activity," notes Daniel Müller, ESA's Solar Orbiter project scientist.

Solar Orbiter is the most complex scientific laboratory ever to study our life-giving star, taking images of the Sun from closer than any spacecraft before and being the first to look at its polar regions.

In February 2025, Solar Orbiter officially began the 'high latitude' part of its journey around the Sun by tilting its orbit to an angle of 17° with respect to the Sun's equator. In contrast, the planets and all other Sun-observing spacecraft orbit in the ecliptic plane, tilted at most 7° from the solar equator.

The only exception to this is the ESA/NASA Ulysses mission (1990-2009), which flew over the Sun's poles but did not carry any imaging instruments. Solar Orbiter's observations will complement Ulysses' by observing the poles for the first time with telescopes, in addition to a full suite of in-situ sensors, while flying much closer to the Sun. Additionally, Solar Orbiter will monitor changes at the poles throughout the solar cycle.

Solar Orbiter will continue to orbit around the Sun at this tilt angle until 24 December 2026, when its next flight past Venus will tilt its orbit to 24°. From 10 June 2029, the spacecraft will orbit the Sun at an angle of 33°. (Overview of Solar Orbiter's journey around the Sun.)

Solar Orbiter is a space mission of international collaboration between ESA and NASA, operated by ESA. Solar Orbiter's Polarimetric and Helioseismic Imager (PHI) instrument is led by the Max Planck Institute for Solar System Research (MPS), Germany. The Extreme Ultraviolet Imager (EUI) instrument is led by the Royal Observatory of Belgium (ROB). The Spectral Imaging of the Coronal Environment (SPICE) instrument is a European-led facility instrument, led by the Institut d'Astrophysique Spatiale (IAS) in Paris, France.

Materialsprovided byEuropean Space Agency.Note: Content may be edited for style and length.

The invisible killer: PM 1 pollution uncovered across America

Air pollution causes health problems and is attributable to some 50,000 annual deaths in the United States, but not all air pollutants pack the same punch.

Scientists have tracked the scope of "PM 2.5" pollution over decades. PM 2.5 is a size of "particulate matter" that is less than 2.5 microns in diameter. But less information was available about its even tinier cousin, described as "submicron" or "PM 1" particulate matter, which is less than 1 micron in diameter. Why does that matter? Because the "little guys" might be the source of worse health effects.

With a study now published inThe Lancet Planetary Health, researchers at Washington University in St. Louis have quantified the amount of PM 1 over the United States from the past 25 years.

"This measurement serves as a starting point to understand which pollutants regulators could target to make the most effective health impact," said Randall Martin, the Raymond R. Tucker Distinguished Professor of energy, environmental and chemical engineering in the McKelvey School of Engineering. "This effort builds upon WashU's strengths in satellite remote sensing and modeling atmospheric aerosols that were leveraged in this study," he added.

Chi Li, research assistant professor in Martin's atmospheric composition analysis group, is the first author of the work. Li said these estimates will enable further investigation into both the health and environmental effects of submicron particles.

Li said the very small particles quantified in this study generally come from direct air emissions, such as the black carbon particles released by diesel engines or the smoke from wildfires. Sometimes PM 1 can also form through secondary processes when sulfur dioxide or nitrogen oxides are spit out through fuel combustion and burning coal.

It makes intuitive sense that smaller particles of air pollution could do more damage to the human body because they are able to slip past the body's innate defenses. These submicron particles are at least 6 times smaller than blood cells.

Air particles are not always one single thing, but mixtures of other materials stacked together.

The larger sizes of particles are critically more dominated by components that are not easily modifiable like mineral dust, noted Li.

The researchers were able to calculate their submicron estimates based on the known ratios of what makes up PM 2.5 particles, which include seven main components such as sulfate, nitrate and mineral dust.

"Putting the seven species together, we can calculate the total PM 1 concentration over the country," Li said.

This research sets the stage for further analysis of where, how and why certain types of particles congregate, and how they can affect the environment and human body.

"When EPA first promulgated a fine PM air quality standard in 1997, there was considerable discussion about regulating PM 1 or PM2.5," said Jay Turner, the James McKelvey Professor of Engineering Education and co-author on the study. "For numerous reasons, including but not limited to the lack of health impacts studies for PM 1 compared to studies for PM 2.5, the latter was chosen. This study provides a comprehensive, nationwide dataset to examine PM1 impacts on health."

A next step will involve working with epidemiologists to assess the association of PM 1 with health outcomes.

The new dataset revealed another notable fact: pollution regulation does help. Across the contiguous U.S., average PM 1 levels in the air people breathe dropped sharply from 1998 to 2022, thanks to decades of environmental regulations like the Clean Air Act. However, this progress has slowed since 2010, mainly because of rising wildfire activity. Future pollution controls will need to address emerging, non-fossil fuel sources, study authors said.

Other countries like China have a head start tracking nationwide PM 1, but now the U.S. can quickly catch up.

"This dataset offers unprecedented information for the United States about an important pollutant for which few other measurements exist," Martin said.

Funding from National Institute of Environmental Health Sciences, National Institutes of Health.

Materialsprovided byWashington University in St. Louis. Original written by Leah Shaffer.Note: Content may be edited for style and length.

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